Bree-Anna Burick Sep 16, 2026 2 min read

Bills to Open New Highmark Stadium Thursday Night vs. Lions

Buffalo Bills quarterback Josh Allen (17) celebrates after scoring a touchdown during the game against the Kansas City Chiefs, Sunday, Nov. 17, 2024 in Orchard Park N.Y. The Bills defeated the Chiefs 30-21. (Lauren Bacho via AP)

The Buffalo Bills are about to break in their brand-new home, and they're doing it in front of the whole country. Buffalo will host the Detroit Lions on Thursday Night Football, marking the first regular season game ever played at the new Highmark Stadium.

Both teams are coming in fresh off strong Week 1 performances. The Bills opened their season with a 36-31 win over the Houston Texans, while the Lions survived an overtime battle against the New Orleans Saints. That means Buffalo will be looking to keep the momentum going as it welcomes fans into the new building for the first time, and Detroit will be doing everything it can to spoil the party.

Game Info

  • When: Thursday, Sept. 17

  • Where: Highmark Stadium in Orchard Park, N.Y.

  • What time: 8:15 p.m. ET

What's Ahead for the Bills

After Thursday's showdown with Detroit, Buffalo's schedule keeps rolling with a Week 3 matchup against the Los Angeles Chargers, followed by a Week 4 game at home against the New England Patriots. The Bills will get a bye in Week 7 before a stretch that includes road trips to Minnesota and the Jets, plus a Thanksgiving night matchup against the Kansas City Chiefs at home in Week 12.

For Bills Mafia, Thursday night is shaping up to be one of the most memorable moments of the season. A new stadium, a national audience, and a Lions team that's already proven it won't go down without a fight. It's the kind of night that could set the tone for how the rest of Buffalo's season goes.

Want more NFL coverage? Head to Sports Pass for the latest. And for more stories that keep you informed and entertained, YourLifeBuzz has you covered.

ShareTweetShareEmail
Explore by Topic